REM+ is designed to support and enhance your body's most important regeneration time- Sleep. REM+ features patented and clinically proven ingredients, all designed to improve deep restorative sleep, regulate stress, and support a healthier gut-brain connection*. Its unique combination of ingredients play a crucial role in calming the nervous system, optimizing regenerative sleep cycles, and supporting gut health, which is the foundation of recovery and longevity.

Chronically poor sleep quality accelerates biological aging by disrupting hormone balance, increasing inflammation, and impairing cellular repair. REM+ helps prevent this by enhancing REM (Rapid Eye Movement) and deep sleep cycles (Slow Wave Sleep), reducing nighttime cortisol spikes and restoring circadian rhythm—all of which contribute to slowing “inflammaging” and supporting long-term neurological, metabolic, and immune function.

Definitely. Quality sleep is the foundation for growth hormone release, muscle repair, testosterone regulation, and metabolic function. REM+ helps optimize this nocturnal recovery window by extending deep and REM sleep phases. Additionally, saffron and lemon balm have been linked to reduced cortisol and improved HPA-axis balance—key for athletic performance and recovery.

REM+ uses magnesium glycinate, a highly absorbable form that is chelated to the amino acid Glycine, which is the most effective form of magnesium for calming the nervous system. What sets REM+ apart is its synergistic formulation. Magnesium alone doesn’t have the capacity to positively affect microbiome health, or serotonin/melatonin regulation. The inclusion of Affron® saffron and Relissa® lemon balm works on neurotransmitters and sleep latency, while L. plantarum supports the gut-brain axis, which is critical for building a healthier circadian rhythm and controlling inflammation.

Many people incorporate REM+ into their evening routine to support relaxation and a sense of calm, even beyond sleep support. The combination of our patented Relissa™ phytosomal lemon balm and Affron® patented saffron extract has been studied for its role in supporting balanced neurotransmitter activity and promoting a calm, relaxed state — making it a great fit for those navigating busy, high-demand lifestyles.

We recommend that you take REM+ each night before sleep. Since you do not need to take REM+ with food, you can take it a couple hours after dinner or right before sleeping.

Unlike many sleep aids, REM+ does not disrupt your natural sleep cycles, or leave you feeling groggy the next day. All ingredients are non-habit-forming and designed to restore your body’s intrinsic ability to produce calming neurotransmitters and sleep hormones. In fact, many users find that after consistent use, their sleep improves even on nights they don’t take it.